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Anti-OTUD5/DUBA Polyclonal Antibody
😃Good
Catalog No. TMAB-09833
Anti-OTUD5/DUBA Polyclonal Antibody is a Rabbit antibody targeting OTUD5/DUBA. Anti-OTUD5/DUBA Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-OTUD5/DUBA Polyclonal Antibody
Anti-OTUD5/DUBA Polyclonal Antibody
😃Good
Catalog No. TMAB-09833
Anti-OTUD5/DUBA Polyclonal Antibody is a Rabbit antibody targeting OTUD5/DUBA. Anti-OTUD5/DUBA Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-OTUD5/DUBA Polyclonal Antibody is a Rabbit antibody targeting OTUD5/DUBA. Anti-OTUD5/DUBA Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Chicken,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Tissue Specificity | Expressed in various tissues, including the liver and placenta, as well as in peripheral blood leukocytes. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008] |
| Immunogen | KLH conjugated synthetic peptide: human OTUD5/DUBA |
| Antigen Species | Human |
| Gene Name | OTUD5 |
| Gene ID | |
| Protein Name | OTU domain-containing protein 5 |
| Uniprot ID | |
| Function | Negative regulator of innate immune system. Has deubiquitinating activity that is directed towards 'Lys-63'-linked polyubiquitin chains. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. |
| Molecular Weight | Theoretical: 61 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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