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Anti-Phospho-REC8 (Ser251) Polyclonal Antibody is a Rabbit antibody targeting Phospho-REC8 (Ser251). Anti-Phospho-REC8 (Ser251) Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-Phospho-REC8 (Ser251) Polyclonal Antibody is a Rabbit antibody targeting Phospho-REC8 (Ser251). Anti-Phospho-REC8 (Ser251) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Chromosome. |
| Tissue Specificity | Expressed in testis and thymus. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II. |
| Immunogen | KLH conjugated synthesised phosphopeptide: mouse REC8 around the phosphorylation site of Ser251 |
| Antigen Species | Mouse |
| Gene Name | Rec8 |
| Gene ID | |
| Protein Name | Meiotic recombination protein REC8 homolog |
| Uniprot ID | |
| Function | Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II (By similarity). |
| Molecular Weight | Theoretical: 67 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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