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Anti-GIMAP5 Polyclonal Antibody

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Catalog No. TMAB-06478

Anti-GIMAP5 Polyclonal Antibody is a Rabbit antibody targeting GIMAP5. Anti-GIMAP5 Polyclonal Antibody can be used in WB.

Anti-GIMAP5 Polyclonal Antibody

Anti-GIMAP5 Polyclonal Antibody

😃Good
Catalog No. TMAB-06478
Anti-GIMAP5 Polyclonal Antibody is a Rabbit antibody targeting GIMAP5. Anti-GIMAP5 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-GIMAP5 Polyclonal Antibody is a Rabbit antibody targeting GIMAP5. Anti-GIMAP5 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMitochondrion outer membrane; Single-pass type IV membrane protein (By similarity). Lysosome.
Tissue SpecificityWidely expressed with high levels in lymph node and spleen. High expression found in CD4 and CD8-positive T-cells and monocytes with very low levels in B-lymphocytes. Highly expressed in B-lymphocyte-derived neoplasms.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundGIMAP5, also known as IAN5, IAN4L1 (immunity-associated nucleotide 4-like 1 protein), IAN4, IMAP3, HIMAP3 or IROD, is a 307 amino acid single-pass type IV membrane protein of the mitochondrial outer membrane. A member of the GTP-binding superfamily and the immuno-associated nucleotide (IAN) subfamily, GIMAP5 plays a role in T-cell survival and mitochondrial integrity. GIMAP5 is highly expressed in CD4 and CD8-positive T-cells and monocytes, as well as B-lymphocyte-derived neoplasms. GIMAP5 exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 7q36.1. Defects in the GIMAP5 gene are associated with systemic lupus erythematosus.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human GIMAP5
Antigen Species
Human
Gene Name
GIMAP5
Gene ID
Protein Name
GTPase IMAP family member 5
Uniprot ID
Function
Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence (By similarity).
Chemical Properties
Molecular WeightTheoretical: 35 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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