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Anti-DOPA Decarboxylase Polyclonal Antibody

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Catalog No. TMAB-05284

Anti-DOPA Decarboxylase Polyclonal Antibody is a Rabbit antibody targeting DOPA Decarboxylase. Anti-DOPA Decarboxylase Polyclonal Antibody can be used in WB.

Anti-DOPA Decarboxylase Polyclonal Antibody

Anti-DOPA Decarboxylase Polyclonal Antibody

😃Good
Catalog No. TMAB-05284
Anti-DOPA Decarboxylase Polyclonal Antibody is a Rabbit antibody targeting DOPA Decarboxylase. Anti-DOPA Decarboxylase Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-DOPA Decarboxylase Polyclonal Antibody is a Rabbit antibody targeting DOPA Decarboxylase. Anti-DOPA Decarboxylase Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research Backgroundbs-0180P is one synthetic peptide derived from human DDC. DOPA decarboxylase is an enzyme implicated in 2 metabolic pathways, synthesizing 2 important neurotransmitters: dopamine and serotonin which both play key roles in many clinical disorders, including Parkinson's disease. Following the hydroxylation of tyrosine to form L dihydroxyphenylalanine (LDOPA), catalyzed by tyrosine hydroxylase, DDC decarboxylates LDOPA to form dopamine. This neurotransmitter is found in different areas of the brain and is particularly abundant in basal ganglia. Dopamine is also produced by DDC in the sympathetic nervous system and is the precursor of the catecholaminergic hormones, noradrenaline and adrenaline in the adrenal medulla. In the nervous system, tryptophan hydroxylase produces 5 OH tryptophan, which is decarboxylated by DDC, giving rise to serotonin. DDC is a homodimeric, pyridoxal phosphate dependent enzyme.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human DDC
Antigen Species
Human
Gene Name
DDC
Gene ID
1644
Protein Name
Aromatic-L-amino-acid decarboxylase
Uniprot ID
P20711
Function
Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
Chemical Properties
Molecular WeightTheoretical: 53 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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