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Anti-PI-15 Polyclonal Antibody

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Catalog No. TMAB-11426

Anti-PI-15 Polyclonal Antibody is a Rabbit antibody targeting PI-15. Anti-PI-15 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-PI-15 Polyclonal Antibody

Anti-PI-15 Polyclonal Antibody

😃Good
Catalog No. TMAB-11426
Anti-PI-15 Polyclonal Antibody is a Rabbit antibody targeting PI-15. Anti-PI-15 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PI-15 Polyclonal Antibody is a Rabbit antibody targeting PI-15. Anti-PI-15 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
Tissue SpecificityWeakly expressed. Expressed at low level in prostate, mammary gland, salivary gland and thyroid gland.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundCysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP-8 (Cysteine-rich secretory protein 8), also known as PI15 (Peptidase inhibitor 15), P25TI or SugarCrisp, is a 258 amino acid secreted protein that belongs to the CRISP family. Expressed at low levels in thyroid, prostate, salivary and mammary tissue, CRISP-8 functions as a serine protease inhibitor that exhibits weak inhibitory action against Trypsin, a serine protease found in the digestive system. In addition to its role as a protease inhibitor, CRISP-8 is secreted in neuroblastoma and glioblastoma cell lines, suggesting a role for CRISP-8 in tumor formation and metastasis within the central nervous system.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PI-15
Antigen Species
Human
Gene Name
PI15
Gene ID
51050
Protein Name
Peptidase inhibitor 15
Uniprot ID
O43692
Function
The soybean trypsin inhibitor was first crystallized by Kunitz in 1945 and is Serine protease inhibitor which displays weak inhibitory activity against trypsin.
Chemical Properties
Molecular WeightTheoretical: 23 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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