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Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody

Catalog No. TMAB-11201 Copy Product Info
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Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTPN7 (Ser246). Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody can be used in WB.

Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-11201

Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTPN7 (Ser246). Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody can be used in WB.

Anti-Phospho-PTPN7
(Ser246) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTPN7 (Ser246). Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Rat)
Verified Activity
Sample: Spleen (Mouse) Lysate at 40 μg
Primary: Anti-phospho-PTPN7 (Ser246) (TMAB-11201) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40 kD
Observed band size: 48 kD
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
Tissue SpecificityExpressed exclusively in thymus and spleen.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: mouse PTPN7 around the phosphorylation site of Ser246
Antigen Species
Mouse
Gene Name
PTPN7
Gene ID
320139
Protein Name
Tyrosine-protein phosphatase non-receptor type 7
Uniprot ID
Q8BUM3
Function
Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction.
Chemical Properties
Molecular WeightTheoretical: 40 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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