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Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody
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Catalog No. TMAB-11201
Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTPN7 (Ser246). Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody can be used in WB.
Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody
Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody
😃Good
Catalog No. TMAB-11201
Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTPN7 (Ser246). Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTPN7 (Ser246). Anti-Phospho-PTPN7 (Ser246) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | Expressed exclusively in thymus and spleen. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: mouse PTPN7 around the phosphorylation site of Ser246 |
| Antigen Species | Mouse |
| Gene Name | PTPN7 |
| Gene ID | |
| Protein Name | Tyrosine-protein phosphatase non-receptor type 7 |
| Uniprot ID | |
| Function | Protein phosphatase that acts preferentially on tyrosine-phosphorylated MAPK1. Plays a role in the regulation of T and B-lymphocyte development and signal transduction. |
| Molecular Weight | Theoretical: 40 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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