Anti-PBXIP1 Polyclonal Antibody is a Rabbit antibody targeting PBXIP1. Anti-PBXIP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

IgG

Human (predicted:Mouse,Rat,Pig,Cow,Horse,Sheep)

IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500

Polyclonal

KLH conjugated synthetic peptide: human PBXIP1

Human

PBXIP1

Pre-B-cell leukemia transcription factor-interacting protein 1

Regulator of pre-B-cell leukemia transcription factors (BPXs) function. Inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. Tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.3 PublicationsManually curated information for which there is published experimental evidence. More… Manual assertion based on experiment ini
Ref.1"Functional cloning and characterization of a novel nonhomeodomain protein that inhibits the binding of PBX1-HOX complexes to DNA."
Abramovich C., Shen W.-F., Pineault N., Imren S., Montpetit B., Largman C., Humphries R.K.
J. Biol. Chem. 275:26172-26177(2000) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, TISSUE SPECIFICITY, SUBCELLULAR LOCATION, INTERACTION WITH PBX1; PBX2 AND PBX3, VARIANT ASP-357. Ref.6"Functional characterization of multiple domains involved in the subcellular localization of the hematopoietic Pbx interacting protein (HPIP)."
Abramovich C., Chavez E.A., Lansdorp P.M., Humphries R.K.
Oncogene 21:6766-6771(2002) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, CHARACTERIZATION, SUBCELLULAR LOCATION. Ref.8"An inherent role of microtubule network in the action of nuclear receptor."
Manavathi B., Acconcia F., Rayala S.K., Kumar R.
Proc. Natl. Acad. Sci. U.S.A. 103:15981-15986(2006) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, SUBCELLULAR LOCATION, INTERACTION WITH ESR1, MUTAGENESIS OF 615-LEU--LEU-619.