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Anti-CATSPERB Polyclonal Antibody
😃Good
Catalog No. TMAB-03699
Anti-CATSPERB Polyclonal Antibody is a Rabbit antibody targeting CATSPERB. Anti-CATSPERB Polyclonal Antibody can be used in WB.
Anti-CATSPERB Polyclonal Antibody
Anti-CATSPERB Polyclonal Antibody
😃Good
Catalog No. TMAB-03699
Anti-CATSPERB Polyclonal Antibody is a Rabbit antibody targeting CATSPERB. Anti-CATSPERB Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Antigen Details
Chemical Properties
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| Description | Anti-CATSPERB Polyclonal Antibody is a Rabbit antibody targeting CATSPERB. Anti-CATSPERB Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Multi-pass membrane protein |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | CatSpers are ion transport proteins located on the surface of sperm cells in the principal piece of the sperm tail. CatSpers are vital to sperm motility, fertilization and cAMP-mediated calcium influx in sperm. There are four CatSper proteins in mammalian sperm, namely CatSper (or CatSper1), CatSper2, CatSper3 and CatSper4. CatSper proteins are believed to assemble into a heterotetrameric complex, forming an alkalinization-activated Ca2+-selective channel. CatSper∫ is a multipass membrane protein that functions as an auxiliary protein of the CatSper channel. It contains a large extracellular domain and a number of N-glycosylation sites. CatSper∫ specifically interacts with CatSper1 and through this interaction plays an important role in the hyperactivated motility of sperm cells, a process that is required in the preparation of sperm for fertilization. |
| Immunogen | KLH conjugated synthetic peptide: human CATSPERB |
| Antigen Species | Human |
| Gene Name | CATSPERB |
| Gene ID | |
| Protein Name | Cation channel sperm-associated protein subunit beta |
| Uniprot ID | |
| Function | RelevanceCATSPERB is a component of a complex composed at least of CATSPER1, CATSPERB, CATSPERG and HSPA1B. CATSPERB contains at least 2 transmembrane domains and 8 N-glycosylation sites. CATSPERB is required for trafficking or formation of a stable channel complex. It is involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. There are 2 isoforms produced by alternative splicing. |
| Molecular Weight | Theoretical: 127 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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