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Anti-SLCO2A1 Polyclonal Antibody

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Catalog No. TMAB-12919

Anti-SLCO2A1 Polyclonal Antibody is a Rabbit antibody targeting SLCO2A1. Anti-SLCO2A1 Polyclonal Antibody can be used in WB,FCM.

Anti-SLCO2A1 Polyclonal Antibody

Anti-SLCO2A1 Polyclonal Antibody

Copy Product Info
😃Good
Catalog No. TMAB-12919
Anti-SLCO2A1 Polyclonal Antibody is a Rabbit antibody targeting SLCO2A1. Anti-SLCO2A1 Polyclonal Antibody can be used in WB,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-SLCO2A1 Polyclonal Antibody is a Rabbit antibody targeting SLCO2A1. Anti-SLCO2A1 Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat)
Verified Activity
1. Blank control: Mouse kidney.
Primary Antibody (green line): Rabbit Anti-SLCO2A1 antibody (TMAB-12919)
Dilution: 3 μg /10^6 cells;
Isotype Control Antibody (orange line): Rabbit IgG.
Secondary Antibody: Goat anti-rabbit IgG-PE
Dilution: 1 μg /test.
Protocol
The cells were incubated in 5% BSA to block non-specific protein-protein interactions for 30 min at at room temperature. Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
2. Sample: Kidney (Mouse) Lysate at 40 μg
Primary: Anti-SLCO2A1 (TMAB-12919) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 70 kD
Observed band size: 75 kD
Application
Recommended Dose
WB: 1:500-2000; FCM: 3μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
Tissue SpecificityUbiquitous.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe organic anion transporting polypeptide (OATP) family of proteins play a role in drug absorption, distribution and excretion. OATP proteins mediate the uptake of a broad range of substrates, including bile salts, hormones, drugs and antibiotics, and they are expressed in various tissues, such as gut, brain, kidney and liver. PGT, also known as SLCO2A1 (solute carrier organic anion transporter family, member 2A1), SLC21A2 or OATP2A1, is a 643 amino acid multi-pass membrane protein that belongs to the organic anion transporter family. Expressed ubiquitously, PGT is thought to mediate the release, transepithelial transport and clearance of prostaglandins from cells to other areas of the body. The gene encoding PGT maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PGT/Slco2a1
Antigen Species
Human
Gene Name
SLCO2A1
Gene ID
Protein Name
Solute carrier organic anion transporter family member 2A1
Uniprot ID
Function
May mediate the release of newly synthesized prostaglandins from cells, the transepithelial transport of prostaglandins, and the clearance of prostaglandins from the circulation. Transports PGD2, as well as PGE1, PGE2 and PGF2A.
Chemical Properties
Molecular WeightTheoretical: 70 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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