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Anti-TMEM106B Polyclonal Antibody
Catalog No. TMAB-13587 Copy Product Info
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Anti-TMEM106B Polyclonal Antibody is a Rabbit antibody targeting TMEM106B. Anti-TMEM106B Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-TMEM106B Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-13587
Anti-TMEM106B Polyclonal Antibody is a Rabbit antibody targeting TMEM106B. Anti-TMEM106B Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-TMEM106B Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-TMEM106B Polyclonal Antibody is a Rabbit antibody targeting TMEM106B. Anti-TMEM106B Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse,Dog) |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (rat heart); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (TMEM106B) Polyclonal Antibody, Unconjugated (TMAB-13587) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded (human brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (TMEM106B) Polyclonal Antibody, Unconjugated (TMAB-13587) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 3. Paraformaldehyde-fixed, paraffin embedded (human stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (TMEM106B) Polyclonal Antibody, Unconjugated (TMAB-13587) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 4. Sample: Lane 1: Recombinant human TMEM106B protein, N-Trx-His Primary: Anti-TMEM106B (TMAB-13587) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31 kDa Observed band size: 32 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:400-800; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Late endosome membrane; Single-pass type II membrane protein. Lysosome membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Expressed in frontal cortex. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | TMEM106B is a 274 amino acid single-pass membrane protein that is encoded by a gene which maps to human chromosome 7. Chromosome 7 houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders, including cases of acute myelogenous leukemia and myelodysplasia. |
| Immunogen | KLH conjugated synthetic peptide: human TMEM106B |
| Antigen Species | Human |
| Gene Name | TMEM106B |
| Gene ID | |
| Protein Name | Transmembrane protein 106B |
| Uniprot ID |
| Molecular Weight | Theoretical: 31 kDa. Actual: 32 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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