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Anti-COL6A5 Polyclonal Antibody

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Catalog No. TMAB-04517

Anti-COL6A5 Polyclonal Antibody is a Rabbit antibody targeting COL6A5. Anti-COL6A5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-COL6A5 Polyclonal Antibody

Anti-COL6A5 Polyclonal Antibody

Copy Product Info
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Catalog No. TMAB-04517
Anti-COL6A5 Polyclonal Antibody is a Rabbit antibody targeting COL6A5. Anti-COL6A5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-COL6A5 Polyclonal Antibody is a Rabbit antibody targeting COL6A5. Anti-COL6A5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human)
Verified Activity
Tissue/cell: rat skin tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min;
Incubation: Anti-COL6A5/Collagen VI alpha 5 Polyclonal Antibody, Unconjugated (TMAB-04517) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted, extracellular space, extracellular matrix. Note=Deposed in the extracellular matrix of skeletal muscle.
Tissue SpecificityExpressed in skin, followed by lung, small intestine, colon and testis. In skin, it is expressed in the epidermis with strongest staining in suprabasal viable layers. In ATOD patients, it is absent in the most differentiated upper spinous and granular layers (at protein level).
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a collagen that contains N- and C-terminal von Willebrand factor A-like domains. The encoded protein may interact with the alpha 1 and alpha 2 chains of collagen VI to form the complete collagen VI trimer. Sequence polymorphisms in this gene have been linked to atopic dermatitis (eczema). Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human COL6A5/Collagen VI alpha 5
Antigen Species
Human
Gene Name
COL6A5
Gene ID
Protein Name
Collagen alpha-5(VI) chain
Uniprot ID
Function
Collagen VI acts as a cell-binding protein.
Chemical Properties
Molecular WeightTheoretical: 288 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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