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Anti-Phospho-TEM8 (Tyr382) Polyclonal Antibody
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Catalog No. TMAB-11368
Anti-Phospho-TEM8 (Tyr382) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TEM8 (Tyr382). Anti-Phospho-TEM8 (Tyr382) Polyclonal Antibody can be used in WB.
Anti-Phospho-TEM8 (Tyr382) Polyclonal Antibody
Anti-Phospho-TEM8 (Tyr382) Polyclonal Antibody
😃Good
Catalog No. TMAB-11368
Anti-Phospho-TEM8 (Tyr382) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TEM8 (Tyr382). Anti-Phospho-TEM8 (Tyr382) Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-TEM8 (Tyr382) Polyclonal Antibody is a Rabbit antibody targeting Phospho-TEM8 (Tyr382). Anti-Phospho-TEM8 (Tyr382) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Chicken,Pig,Rabbit,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Cell projection, lamellipodium membrane; Single-pass type I membrane protein. Cell projection, filopodium membrane; Single-pass type I membrane protein. Note=At the membrane of lamellipodia and at the tip of actin-enriched filopodia. Colocalizes with actin at the base of lamellipodia. |
| Tissue Specificity | Detected in umbilical vein endothelial cells (at protein level). Highly expressed in tumor endothelial cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008] |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human ANTXR1 around the phosphorylation site of Tyr382 |
| Antigen Species | Human |
| Gene Name | ANTXR1 |
| Gene ID | |
| Protein Name | Anthrax toxin receptor 1 |
| Uniprot ID | |
| Function | Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells. |
| Molecular Weight | Theoretical: 45 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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