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Anti-SPG11 Polyclonal Antibody

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Catalog No. TMAB-13106

Anti-SPG11 Polyclonal Antibody is a Rabbit antibody targeting SPG11. Anti-SPG11 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-SPG11 Polyclonal Antibody

Anti-SPG11 Polyclonal Antibody

Copy Product Info
😃Good
Catalog No. TMAB-13106
Anti-SPG11 Polyclonal Antibody is a Rabbit antibody targeting SPG11. Anti-SPG11 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-SPG11 Polyclonal Antibody is a Rabbit antibody targeting SPG11. Anti-SPG11 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Dog,Pig,Cow)
Verified Activity
1. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (SPG11) Polyclonal Antibody, Unconjugated (TMAB-13106) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded (Human brain glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (SPG11) Polyclonal Antibody, Unconjugated (TMAB-13106) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane. Cytoplasm > cytosol. Nucleus. Mainly cytoplasmic.
Tissue SpecificityExpressed in all structures of brain, with a high expression in cerebellum.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a potential transmembrane protein that is phosphorylated upon DNA damage. Defects in this gene are a cause of spastic paraplegia type 11 (SPG11). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human SPG11
Antigen Species
Human
Gene Name
SPG11
Gene ID
Protein Name
Spatacsin
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 279 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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