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Anti-Phospho-Estrogen Receptor beta (Ser87) Polyclonal Antibody
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Catalog No. TMAB-10679
Anti-Phospho-Estrogen Receptor beta (Ser87) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Estrogen Receptor beta (Ser87). Anti-Phospho-Estrogen Receptor beta (Ser87) Polyclonal Antibody can be used in WB,ICC/IF,FCM.
Anti-Phospho-Estrogen Receptor beta (Ser87) Polyclonal Antibody
Anti-Phospho-Estrogen Receptor beta (Ser87) Polyclonal Antibody
😃Good
Catalog No. TMAB-10679
Anti-Phospho-Estrogen Receptor beta (Ser87) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Estrogen Receptor beta (Ser87). Anti-Phospho-Estrogen Receptor beta (Ser87) Polyclonal Antibody can be used in WB,ICC/IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-Estrogen Receptor beta (Ser87) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Estrogen Receptor beta (Ser87). Anti-Phospho-Estrogen Receptor beta (Ser87) Polyclonal Antibody can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Rabbit,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Tissue specificityIsoform beta-1 is expressed in testis and ovary, and at a lower level in heart, brain, placenta, liver, skeletal muscle, spleen, thymus, prostate, colon, bone marrow, mammary gland and uterus. Also found in uterine bone, breast, and ovarian tumor cell lines, but not in colon and liver tumors. Isoform beta-2 is expressed in spleen, thymus, testis and ovary and at a lower level in skeletal muscle, prostate, colon, small intestine, leukocytes, bone marrow, mammary gland and uterus. Isoform beta-3 is found in testis. Isoform beta-4 is expressed in testis, and at a lower level in spleen, thymus, ovary, mammary gland and uterus. Isoform beta-5 is expressed in testis, placenta, skeletal muscle, spleen and leukocytes, and at a lower level in heart, lung, liver, kidney, pancreas, thymus, prostate, colon, small intestine, bone marrow, mammary gland and uterus. Not expressed in brain. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the family of estrogenreceptors and superfamily of nuclear receptor transcriptionfactors. The gene product contains an N-terminal DNA binding domainand C-terminal ligand binding domain and is localized to thenucleus, cytoplasm, and mitochondria. Upon binding to17beta-estradiol or related ligands, the encoded protein formshomo- or hetero-dimers that interact with specific DNA sequences toactivate transcription. Some isoforms dominantly inhibit theactivity of other estrogen receptor family members. Severalalternatively spliced transcript variants of this gene have beendescribed, but the full-length nature of some of these variants hasnot been fully characterized. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated synthesised phosphopeptide: human Estrogen Receptor beta around the phosphorylation site of Ser87 |
| Antigen Species | Human |
| Gene Name | ESR2 |
| Gene ID | |
| Protein Name | Estrogen receptor beta |
| Uniprot ID | |
| Function | Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. |
| Molecular Weight | Theoretical: 66 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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