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Anti-PHB2 Polyclonal Antibody

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Catalog No. TMAB-10257 Copy Product Info
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Anti-PHB2 Polyclonal Antibody is a Rabbit antibody targeting PHB2. Anti-PHB2 Polyclonal Antibody can be used in WB,ICC/IF,FCM.
Anti-PHB2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PHB2 Polyclonal Antibody is a Rabbit antibody targeting PHB2. Anti-PHB2 Polyclonal Antibody can be used in WB,ICC/IF,FCM.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Cow,Horse,Sheep)
Application
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:100-500; FCM: 2μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMitochondrion inner membrane. Cytoplasm. Nucleus. Also cytoplasmic and nuclear.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundEnables several functions, including protein C-terminus binding activity; protein N-terminus binding activity; and protein dimerization activity. Involved in several processes, including defense response to virus; positive regulation of cell cycle phase transition; and regulation of transcription, DNA-templated. Located in several cellular components, including cell surface; mitochondrial membrane; and nuclear matrix. Part of mitochondrial prohibitin complex. [provided by Alliance of Genome Resources, Apr 2022]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PHB2
Antigen Species
Human
Gene Name
PHB2
Gene ID
Protein Name
Prohibitin-2
Uniprot ID
Function
Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
Chemical Properties
Molecular WeightTheoretical: 33 kDa. Actual: 35 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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