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Anti-PHB2 Polyclonal Antibody
😃Good
Catalog No. TMAB-10257
Anti-PHB2 Polyclonal Antibody is a Rabbit antibody targeting PHB2. Anti-PHB2 Polyclonal Antibody can be used in WB,ICC/IF,FCM.
Anti-PHB2 Polyclonal Antibody
Anti-PHB2 Polyclonal Antibody
😃Good
Catalog No. TMAB-10257
Anti-PHB2 Polyclonal Antibody is a Rabbit antibody targeting PHB2. Anti-PHB2 Polyclonal Antibody can be used in WB,ICC/IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PHB2 Polyclonal Antibody is a Rabbit antibody targeting PHB2. Anti-PHB2 Polyclonal Antibody can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Cow,Horse,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:100-500; FCM: 2μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion inner membrane. Cytoplasm. Nucleus. Also cytoplasmic and nuclear. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Enables several functions, including protein C-terminus binding activity; protein N-terminus binding activity; and protein dimerization activity. Involved in several processes, including defense response to virus; positive regulation of cell cycle phase transition; and regulation of transcription, DNA-templated. Located in several cellular components, including cell surface; mitochondrial membrane; and nuclear matrix. Part of mitochondrial prohibitin complex. [provided by Alliance of Genome Resources, Apr 2022] |
| Immunogen | KLH conjugated synthetic peptide: human PHB2 |
| Antigen Species | Human |
| Gene Name | PHB2 |
| Gene ID | |
| Protein Name | Prohibitin-2 |
| Uniprot ID | |
| Function | Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging. |
| Molecular Weight | Theoretical: 33 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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