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Anti-Gamma Synuclein Polyclonal Antibody
😃Good
Catalog No. TMAB-06323
Anti-Gamma Synuclein Polyclonal Antibody is a Rabbit antibody targeting Gamma Synuclein. Anti-Gamma Synuclein Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Gamma Synuclein Polyclonal Antibody
Anti-Gamma Synuclein Polyclonal Antibody
😃Good
Catalog No. TMAB-06323
Anti-Gamma Synuclein Polyclonal Antibody is a Rabbit antibody targeting Gamma Synuclein. Anti-Gamma Synuclein Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Gamma Synuclein Polyclonal Antibody is a Rabbit antibody targeting Gamma Synuclein. Anti-Gamma Synuclein Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle. |
| Tissue Specificity | Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The synculein family consists of 3 highly conserved proteins of between 120 and 140 amino acids that share substantial sequence homology. Each has a series of loosely repeated motifs throughout the first 93 amino acids and an acid region toward the C terminal. The proteins are heat stable and relatively soluble. Three synucleins have been identified and termed alpha, beta and gamma synuclein and are located in the neuronal cytosol and enriched in presynaptic terminals,gamma synuclein is also expressed in many other non-neuronal tissues. Although the precise function of the synucleins are unknown a role in membrane plasticity has been suggested. The synucleins have been implicated in a number of diseases. It has been reported that in breast cancer increased expression of gamma synuclein correlates with disease progression. |
| Immunogen | KLH conjugated synthetic peptide: human gamma Synuclein |
| Antigen Species | Human |
| Gene Name | SNCG |
| Gene ID | |
| Protein Name | Gamma-synuclein |
| Uniprot ID | |
| Function | Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases. May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway. |
| Molecular Weight | Theoretical: 13.5 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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