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Anti-Scavenger Receptor BII Polyclonal Antibody

Catalog No. TMAB-12564 Copy Product Info
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Anti-Scavenger Receptor BII Polyclonal Antibody is a Rabbit antibody targeting Scavenger Receptor BII. Anti-Scavenger Receptor BII Polyclonal Antibody can be used in WB.

Anti-Scavenger Receptor BII Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-12564

Anti-Scavenger Receptor BII Polyclonal Antibody is a Rabbit antibody targeting Scavenger Receptor BII. Anti-Scavenger Receptor BII Polyclonal Antibody can be used in WB.

Anti-Scavenger Receptor BII Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Scavenger Receptor BII Polyclonal Antibody is a Rabbit antibody targeting Scavenger Receptor BII. Anti-Scavenger Receptor BII Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit)
Verified Activity
Sample: Hela Cell (Human) Lysate at 40 μg
Primary: Anti-Scavenger Receptor BII (TMAB-12564) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kD
Observed band size: 52 kD
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationLysosome membrane; Multi-pass membrane protein.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundHigh density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SR-BI and SR-BII (previously known as SR-BI.2) are the alternatively spliced products of a single gene. SR-BII and SR-BI are identical except for the encoded c-terminal cytoplasmic domain. Both SR-BI and SR-BII bind HDL and mediates selective uptake of HDL cholesteryl ester, but with SR-BII having an approximately 4-fold lower efficiency than SR-BI. SR-BI and SR-BII are expressed primarily in liver and non-placental steroidgenic tissues. Although the role of these scavenger receptors is not completely clear, SR-BII mRNA results from the alternative splicing of SR-BI precursor transcripts with both isoforms mediating selective transfer of lipid between HDL and cells. Therefore, the relative expression and functional activities of these two isoforms create a potential means of regulating selective lipid transfer between HDL and cells.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Scavenger Receptor BII
Antigen Species
Human
Gene Name
SCARB2
Gene ID
950
Protein Name
Lysosome membrane protein 2
Uniprot ID
Q14108
Function
Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting.
Chemical Properties
Molecular WeightTheoretical: 52 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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