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Anti-KCNT1 Polyclonal Antibody

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Catalog No. TMAB-07954

Anti-KCNT1 Polyclonal Antibody is a Rabbit antibody targeting KCNT1. Anti-KCNT1 Polyclonal Antibody can be used in WB.

Anti-KCNT1 Polyclonal Antibody

Anti-KCNT1 Polyclonal Antibody

😃Good
Catalog No. TMAB-07954
Anti-KCNT1 Polyclonal Antibody is a Rabbit antibody targeting KCNT1. Anti-KCNT1 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-KCNT1 Polyclonal Antibody is a Rabbit antibody targeting KCNT1. Anti-KCNT1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane.
Tissue SpecificityHighest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
FormulationPreservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
Concentration1mg/ml
Research BackgroundPotassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human KCNT1
Antigen Species
Human
Gene Name
KCNT1
Gene ID
57582
Protein Name
Potassium channel subfamily T member 1
Uniprot ID
Q5JUK3
Function
Outwardly rectifying potassium channel subunit that may co-assemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro).
Chemical Properties
Molecular WeightTheoretical: 137 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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