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Anti-BHLHE41 Polyclonal Antibody

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Catalog No. TMAB-03136

Anti-BHLHE41 Polyclonal Antibody is a Rabbit antibody targeting BHLHE41. Anti-BHLHE41 Polyclonal Antibody can be used in WB.

Anti-BHLHE41 Polyclonal Antibody

Anti-BHLHE41 Polyclonal Antibody

😃Good
Catalog No. TMAB-03136
Anti-BHLHE41 Polyclonal Antibody is a Rabbit antibody targeting BHLHE41. Anti-BHLHE41 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-BHLHE41 Polyclonal Antibody is a Rabbit antibody targeting BHLHE41. Anti-BHLHE41 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Dog,Pig,Cow)
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityHighly expressed in skeletal muscle and brain, moderately expressed in pancreas and heart, weakly expressed in placenta, lung, liver and kidney.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundDEC1 is a 412 amino acid, basic helix-loop-helix (bHLH) containing protein that is involved in the control of proliferation and/or differentiation of several cell types including nerve cells, fibroblasts and chondrocytes. The bHLH region of DEC1 is structurally similar to the bHLH regions of the mammalian HES family, Drosophila hairy and Drosophila Enhancer of split m7. DEC1 is a novel direct target for cAMP in a wide range of cells, and is involved in the control of gene expression in cAMP-activated cells. DEC2, also known as SHARP1, is highly expressed in skeletal muscle and brain. The gene encoding human DEC2 maps to chromosome 12p11.23-p12.1. DEC1 and DEC2 play a role in regulating the mammalian molecular clock by suppressing the transcription of specific clock genes. Both DEC1 and DEC2 are detected in the suprachiasmimc nucleus in a circadian fashion. Brief light impulses induce the expression of DEC1 in a phase-dependent manner.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human SHARP1/DEC2
Antigen Species
Human
Gene Name
BHLHE41
Gene ID
79365
Protein Name
Class E basic helix-loop-helix protein 41
Uniprot ID
Q9C0J9
Function
May be a transcriptional repressor that represses both basal and activated transcription.
Chemical Properties
Molecular WeightTheoretical: 50 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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