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Anti-DNA Ligase 1 Polyclonal Antibody
😃Good
Catalog No. TMAB-05208
Anti-DNA Ligase 1 Polyclonal Antibody is a Rabbit antibody targeting DNA Ligase 1. Anti-DNA Ligase 1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-DNA Ligase 1 Polyclonal Antibody
Anti-DNA Ligase 1 Polyclonal Antibody
😃Good
Catalog No. TMAB-05208
Anti-DNA Ligase 1 Polyclonal Antibody is a Rabbit antibody targeting DNA Ligase 1. Anti-DNA Ligase 1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-DNA Ligase 1 Polyclonal Antibody is a Rabbit antibody targeting DNA Ligase 1. Anti-DNA Ligase 1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse,Dog,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Eukaryotic DNA ligases are ATP-dependent enzymes that catalyse the joining of single and double-strand DNA breaks, which is an essential final step in DNA replication, recombination and repair. Four biochemically distinct DNA ligases, termed ligases I-IV, have been identified in mammalian cells. DNA ligase I is functionally homologous to the DNA ligase encoded by the Saccharomyces cerevisiae Cdc9 gene. The joining of Okazaki fragments during lagging strand DNA replication in mammalian cells is due to DNA ligase I. |
| Immunogen | KLH conjugated synthetic peptide: human DNA Ligase 1 |
| Antigen Species | Human |
| Gene Name | LIG1 |
| Gene ID | |
| Protein Name | DNA ligase 1 |
| Uniprot ID | |
| Function | DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. |
| Molecular Weight | Theoretical: 101 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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