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Anti-JLP/MAX binding protein Polyclonal Antibody
Catalog No. TMAB-07869 Copy Product Info
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Anti-JLP/MAX binding protein Polyclonal Antibody is a Rabbit antibody targeting JLP/MAX binding protein. Anti-JLP/MAX binding protein Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-JLP/MAX binding protein Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-07869
Anti-JLP/MAX binding protein Polyclonal Antibody is a Rabbit antibody targeting JLP/MAX binding protein. Anti-JLP/MAX binding protein Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-JLP/MAX binding protein Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-JLP/MAX binding protein Polyclonal Antibody is a Rabbit antibody targeting JLP/MAX binding protein. Anti-JLP/MAX binding protein Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Chicken,Dog,Horse,Sheep) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (JLP MAX binding protein) Polyclonal Antibody, Unconjugated (TMAB-07869) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Cytoplasm, perinuclear region. Note: Perinuclear distribution in response to stress signals such as UV radiation. |
| Tissue Specificity | Isoform 5 is expressed only in testis on the round spermatids of stage I, II and II. Isoform 5 is absent in spermatogonia and spermatocyte. Isoform 3 is expressed in testis. Isoform 4 is expressed in testis and in acute myeloid leukemia (AML) patients. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | JIP-4 is a 1,321 amino acid protein encoded by the human gene SPAG9. It contains a large N-terminal extracellular domain, a short transmembrane helical domain, and a cytoplasmic domain. There are 6 N-glycosylation sites, several phosphorylation sites for cAMP/cGMP-dependent protein kinase, protein kinase C, and casein kinase II, and 10 putative myristoylation sites. There is also a leucine zipper motif, with 6 leucine repeats, that may aid in dimerization since there is no upstream basic domain characteristic of DNA binding proteins. The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. JIP-4 is a cytoplasmic, perinuclear protein that has eight known isoforms whose expression varies by tissue and disease state. |
| Immunogen | KLH conjugated synthetic peptide: human JLP/JIP-4 |
| Antigen Species | Human |
| Gene Name | SPAG9 |
| Gene ID | |
| Protein Name | C-Jun-amino-terminal kinase-interacting protein 4 |
| Uniprot ID | |
| Function | JLP is a member of the JNK-interacting protein (JIP) group of scaffold proteins which selectively mediate JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. |
| Molecular Weight | Theoretical: 146 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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