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Anti-FGF1 Polyclonal Antibody
😃Good
Catalog No. TMAB-05981
Anti-FGF1 Polyclonal Antibody is a Rabbit antibody targeting FGF1. Anti-FGF1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-FGF1 Polyclonal Antibody
Anti-FGF1 Polyclonal Antibody
😃Good
Catalog No. TMAB-05981
Anti-FGF1 Polyclonal Antibody is a Rabbit antibody targeting FGF1. Anti-FGF1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-FGF1 Polyclonal Antibody is a Rabbit antibody targeting FGF1. Anti-FGF1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Pig,Horse,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytosol. Nucleus. Note=Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1 (By similarity). Binding of exogenous FGF1 to FGFR facilitates endocytosis followed by translocation of FGF1 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as LRRC59. |
| Tissue Specificity | Predominantly expressed in kidney and brain. Detected at much lower levels in heart and skeletal muscle. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | FGF1 also designated Heparin-binding growth factor 1 precursor (HBGF-1) ; Acidic fibroblast growth factor (aFGF). heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors. Subunit si monomer.FGF1 belongs to the heparin-binding growth factors family. may play a role in neurite outgrowth; may regulate cell differentiation in the nervous system; may act in synergy with fibronectin to enhance neuronal cell adhesion. |
| Immunogen | KLH conjugated synthetic peptide: human FGF1 |
| Antigen Species | Human |
| Gene Name | FGF1 |
| Gene ID | |
| Protein Name | Fibroblast growth factor 1 |
| Uniprot ID | |
| Function | The heparin-binding fibroblast growth factors play important roles in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. They are potent mitogens in vitro. |
| Molecular Weight | Theoretical: 16 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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