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Anti-TNFRSF10A Polyclonal Antibody 3

Catalog No. TMAB-13633 Copy Product Info
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Anti-TNFRSF10A Polyclonal Antibody 3 is a Rabbit antibody targeting TNFRSF10A. Anti-TNFRSF10A Polyclonal Antibody 3 can be used in WB.

Anti-TNFRSF10A Polyclonal Antibody 3

Copy Product Info
🥰Excellent
Catalog No. TMAB-13633

Anti-TNFRSF10A Polyclonal Antibody 3 is a Rabbit antibody targeting TNFRSF10A. Anti-TNFRSF10A Polyclonal Antibody 3 can be used in WB.

Anti-TNFRSF10A Polyclonal Antibody 3
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-TNFRSF10A Polyclonal Antibody 3 is a Rabbit antibody targeting TNFRSF10A. Anti-TNFRSF10A Polyclonal Antibody 3 can be used in WB.
Ig Type
IgG
Reactivity
Human
Verified Activity
Sample:
Lane 1: Recombinant human DR4 protein, C-His
Primary: Anti-TNFRSF10A (TMAB-13633) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 48 kDa
Observed band size: 23 kDa
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
Tissue SpecificityWidely expressed. High levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K562 erythroleukemia cells, MCF7 breast carcinoma cells and activated T-cells.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
Recombinant Protein: human DR4 protein
Antigen Species
Human
Gene Name
TNFRSF10A
Gene ID
Protein Name
Tumor necrosis factor receptor superfamily member 10A
Uniprot ID
Function
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
Chemical Properties
Molecular WeightTheoretical: 48 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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