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Anti-SAE2/UBA2 Polyclonal Antibody
😃Good
Catalog No. TMAB-12473
Anti-SAE2/UBA2 Polyclonal Antibody is a Rabbit antibody targeting SAE2/UBA2. Anti-SAE2/UBA2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-SAE2/UBA2 Polyclonal Antibody
Anti-SAE2/UBA2 Polyclonal Antibody
😃Good
Catalog No. TMAB-12473
Anti-SAE2/UBA2 Polyclonal Antibody is a Rabbit antibody targeting SAE2/UBA2. Anti-SAE2/UBA2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-SAE2/UBA2 Polyclonal Antibody is a Rabbit antibody targeting SAE2/UBA2. Anti-SAE2/UBA2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Horse,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010] |
| Immunogen | KLH conjugated synthetic peptide: human SAE2 |
| Antigen Species | Human |
| Gene Name | UBA2 |
| Gene ID | |
| Protein Name | SUMO-activating enzyme subunit 2 |
| Uniprot ID | |
| Function | The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. |
| Molecular Weight | Theoretical: 71 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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