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Anti-RNF141/ZNF230 Polyclonal Antibody
😃Good
Catalog No. TMAB-12295
Anti-RNF141/ZNF230 Polyclonal Antibody is a Rabbit antibody targeting RNF141/ZNF230. Anti-RNF141/ZNF230 Polyclonal Antibody can be used in WB.
Anti-RNF141/ZNF230 Polyclonal Antibody
Anti-RNF141/ZNF230 Polyclonal Antibody
😃Good
Catalog No. TMAB-12295
Anti-RNF141/ZNF230 Polyclonal Antibody is a Rabbit antibody targeting RNF141/ZNF230. Anti-RNF141/ZNF230 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-RNF141/ZNF230 Polyclonal Antibody is a Rabbit antibody targeting RNF141/ZNF230. Anti-RNF141/ZNF230 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane |
| Tissue Specificity | soform 1 is testis-specific. Isoform 2 is expressed in heart, brain, skeletal muscle, kidney and pancreas. Isoform 1 is not expressed in fetus or in azoospermic patients. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF141 (ring finger protein 141), also known as ZFP26 or ZNF230, is a 230 amino acid protein that contains one RING-type zinc finger. Expressed as two isoforms (isoform 1 and isoform 2) due to alternative splicing events, RNF141 is thought to function as a transcription factor during spermatogenesis. While isoform 2 is expressed in brain, heart, pancreas, kidney and skeletal muscle, isoform 1 is expressed primarily in testis, suggesting that isoform 1 functions during spermatogenesis. In addition, RNF141 is not expressed in azoospermic (infertile) men, further implicating an important role for RNF141 in testis development and male fertility. |
| Immunogen | KLH conjugated synthetic peptide: human ZNF230/RNF141 |
| Antigen Species | Human |
| Gene Name | RNF141 |
| Gene ID | |
| Protein Name | RING finger protein 141 |
| Uniprot ID | |
| Function | May be involved in spermatogenesis. |
| Molecular Weight | Theoretical: 26 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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