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Anti-CX3CL1 Polyclonal Antibody

Catalog No. TMAB-04795 Copy Product Info
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Anti-CX3CL1 Polyclonal Antibody is a Rabbit antibody targeting CX3CL1. Anti-CX3CL1 Polyclonal Antibody can be used in WB.

Anti-CX3CL1 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-04795

Anti-CX3CL1 Polyclonal Antibody is a Rabbit antibody targeting CX3CL1. Anti-CX3CL1 Polyclonal Antibody can be used in WB.

Anti-CX3CL1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CX3CL1 Polyclonal Antibody is a Rabbit antibody targeting CX3CL1. Anti-CX3CL1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human
Verified Activity
Sample:
Lane 1: Human HepG2 cell lysates
Lane 2: Human SH-SY5Y cell lysates
Lane 3: Human U251 cell lysates
Lane 4: Human A549 cell lysates
Lane 5: Human Huvec cell lysates
Primary: Anti-CX3CL1 (TMAB-04795) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 41 kD
Observed band size: 95 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Single-pass type I membrane protein. Processed fractalkine: Secreted.
Tissue SpecificitySmall intestine, colon, testis, prostate, heart, brain, lung, skeletal muscle, kidney and pancreas.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundCX3CL1 is a member of the delta chemokine subfamily that contains a unique CX3C cysteine motif near the N-terminal. Unlike other known chemokines, it is a type 1 membrane protein containing a chemokine domain tethered on a long mucin-like stalk. CX3CL1, a leukocyte chemoattractant, is expressed in various tissues including the brain, heart, lung, kidney, skeletal muscle, and testis. The expression is reported to be up-regulated in endothelial cells and microglia by inflammatory signals. CX3CR1, a specific receptor for fractalkine, mediates both leukocyte migration and adhesion.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CX3CL1
Antigen Species
Human
Gene Name
CX3CL1
Gene ID
Protein Name
Fractalkine
Uniprot ID
Function
The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.
Chemical Properties
Molecular WeightTheoretical: 41 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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