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Anti-FYCO1 Polyclonal Antibody

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Catalog No. TMAB-06224

Anti-FYCO1 Polyclonal Antibody is a Rabbit antibody targeting FYCO1. Anti-FYCO1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-FYCO1 Polyclonal Antibody

Anti-FYCO1 Polyclonal Antibody

😃Good
Catalog No. TMAB-06224
Anti-FYCO1 Polyclonal Antibody is a Rabbit antibody targeting FYCO1. Anti-FYCO1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-FYCO1 Polyclonal Antibody is a Rabbit antibody targeting FYCO1. Anti-FYCO1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Pig)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasmic vesicle, autophagosome. Endosome. Lysosome. Note=Localizes to the external but not to the internal membrane of autophagosomes, and upon autophagosome/late endosome/lysosome fusion, it stays on the external surface of autolysosomes.
Tissue SpecificityExpressed in heart and skeletal muscle.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundFYCO1 is a 1,478 amino acid protein that contains one RUN domain, one GOLD domain and one FYVE-type zinc finger. Expressed in heart and skeletal muscle, FYCO1 exists as multiple alternatively spliced isoforms and may play a role in transcriptional regulation events. In response to DNA damage, FYCO1 is subject to phosphorylation, probably by ATM or ATR. The gene encoding FYCO1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human FYCO1
Antigen Species
Human
Gene Name
FYCO1
Gene ID
Protein Name
FYVE and coiled-coil domain-containing protein 1
Uniprot ID
Function
May mediate microtubule plus end-directed vesicle transport.
Chemical Properties
Molecular WeightTheoretical: 167 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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