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Anti-ZNF649 Polyclonal Antibody
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Catalog No. TMAB-14402
Anti-ZNF649 Polyclonal Antibody is a Rabbit antibody targeting ZNF649. Anti-ZNF649 Polyclonal Antibody can be used in WB.
Anti-ZNF649 Polyclonal Antibody
Anti-ZNF649 Polyclonal Antibody
😃Good
Catalog No. TMAB-14402
Anti-ZNF649 Polyclonal Antibody is a Rabbit antibody targeting ZNF649. Anti-ZNF649 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-ZNF649 Polyclonal Antibody is a Rabbit antibody targeting ZNF649. Anti-ZNF649 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Highly expressed in heart, skeletal muscle, and brain. Lower expression in liver, lung, kidney, pancreas and placenta. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 649 (ZNF649) is a 505 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZNF649 is highly expressed in heart, brain and skeletal muscle with lower levels of expression in lung, liver, kidney and pancreas. ZNF649 contains ten C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNA-binding and transcriptional repression of mitogen-activated protein kinase signaling pathways. |
| Immunogen | KLH conjugated synthetic peptide: human ZNF649 |
| Antigen Species | Human |
| Gene Name | ZNF649 |
| Gene ID | |
| Protein Name | Zinc finger protein 649 |
| Uniprot ID | |
| Function | Transcriptional repressor. Regulator of transcriptional factor complexes and may suppress SRE and AP-1 transcription activities mediated by growth factor signaling pathways. |
| Molecular Weight | Theoretical: 58 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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