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Anti-beta glucuronidase Polyclonal Antibody

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Catalog No. TMAB-03112

Anti-beta glucuronidase Polyclonal Antibody is a Rabbit antibody targeting beta glucuronidase. Anti-beta glucuronidase Polyclonal Antibody can be used in WB.

Anti-beta glucuronidase Polyclonal Antibody

Anti-beta glucuronidase Polyclonal Antibody

😃Good
Catalog No. TMAB-03112
Anti-beta glucuronidase Polyclonal Antibody is a Rabbit antibody targeting beta glucuronidase. Anti-beta glucuronidase Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-beta glucuronidase Polyclonal Antibody is a Rabbit antibody targeting beta glucuronidase. Anti-beta glucuronidase Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow)
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationLysosome.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundDefects in GUSB are the cause of mucopolysaccharidosis type 7 (MPS7) ; also known as Sly syndrome. MPS7 is an autosomal recessive lysosomal storage disease characterized by inability to degrade glucuronic acid-containing glycosaminoglycans. The phenotype is highly variable, ranging from severe lethal hydrops fetalis to mild forms with survival into adulthood. Most patients with the intermediate phenotype show hepatomegaly, skeletal anomalies, coarse facies, and variable degrees of mental impairment. Mucopolysaccharidosis type 7 is associated with non-immune hydrops fetalis, a generalized edema of the fetus with fluid accumulation in the body cavities due to non-immune causes. Non-immune hydrops fetalis is not a diagnosis in itself but a symptom, a feature of many genetic disorders, and the end-stage of a wide variety of disorders.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human GUSB/beta glucuronidase
Antigen Species
Human
Gene Name
GUSB
Gene ID
2990
Protein Name
beta-glucuronidase
Uniprot ID
P08236
Function
Plays an important role in the degradation of dermatan and keratan sulfates.
Chemical Properties
Molecular WeightTheoretical: 69 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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