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Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2
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Catalog No. TMAB-11314
Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-SPHK2 (Thr614). Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2
Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2
😃Good
Catalog No. TMAB-11314
Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-SPHK2 (Thr614). Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
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Antigen Details
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| Description | Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-SPHK2 (Thr614). Anti-Phospho-SPHK2 (Thr614) Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 1: Cytoplasm. Membrane. Isoform 2: Lysosome membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a kinase that phosphorylates sphingosine into sphingosine-1-phosphate, which is involved in cell differentiation, motility, and apoptosis. The encoded protein plays a role in maintaining cellular levels of sphingosine-1-phosphate. The gene product also enhances apoptosis in different cell types and suppresses cellular proliferation. In mast cells, the encoded protein is necessary for influx of calcium, protein kinase C activation, and cytokine production and degranulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq]. |
| Immunogen | KLH conjugated synthesised phosphopeptide: human SPHK2 around the phosphorylation site of Thr614 |
| Antigen Species | Human |
| Gene Name | SPHK2 |
| Gene ID | |
| Protein Name | Sphingosine kinase 2 |
| Uniprot ID | |
| Function | Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides. |
| Molecular Weight | Theoretical: 72 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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