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Anti-GATA4 Polyclonal Antibody 3

Catalog No. TMAB-06357 Copy Product Info
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Anti-GATA4 Polyclonal Antibody 3 is a Rabbit antibody targeting GATA4. Anti-GATA4 Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.

Anti-GATA4 Polyclonal Antibody 3

Copy Product Info
🥰Excellent
Catalog No. TMAB-06357

Anti-GATA4 Polyclonal Antibody 3 is a Rabbit antibody targeting GATA4. Anti-GATA4 Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.

Anti-GATA4 Polyclonal Antibody 3
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GATA4 Polyclonal Antibody 3 is a Rabbit antibody targeting GATA4. Anti-GATA4 Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Rabbit)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (mouse intestine tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (GATA4) Polyclonal Antibody, Unconjugated (TMAB-06357) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundGATA4 is a 46 kDa member of the GATA family of zinc finger containing transcription factors that is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress induced gene expression in cardiac and smooth muscle cell types. GATA4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain. Serine 105 of GATA4 is phosphorylated in response to agonist stimulation through MEK 1 ERK1 / 2, and weakly through JNK or p38 MAPKs.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human GATA4
Antigen Species
Human
Gene Name
GATA4
Gene ID
Protein Name
Transcription factor GATA-4
Uniprot ID
Function
Transcriptional activator. Binds to the consensus sequence 5'-AGATAG-3'. Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (By similarity). Promotes cardiac myocyte enlargement.
Chemical Properties
Molecular WeightTheoretical: 49 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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