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Anti-EAAT2 Polyclonal Antibody 3
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Catalog No. TMAB-05403
Anti-EAAT2 Polyclonal Antibody 3 is a Rabbit antibody targeting EAAT2. Anti-EAAT2 Polyclonal Antibody 3 can be used in WB.
Anti-EAAT2 Polyclonal Antibody 3
Anti-EAAT2 Polyclonal Antibody 3
Copy Product Info😃Good
Catalog No. TMAB-05403
Anti-EAAT2 Polyclonal Antibody 3 is a Rabbit antibody targeting EAAT2. Anti-EAAT2 Polyclonal Antibody 3 can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Antigen Details
Chemical Properties
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| Description | Anti-EAAT2 Polyclonal Antibody 3 is a Rabbit antibody targeting EAAT2. Anti-EAAT2 Polyclonal Antibody 3 can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat) |
| Verified Activity | Sample: Lane 1: Human U251 cell lysates Lane 2: Human SH-SY5Y cell lysates Lane 3: Human HepG2 cell lysates Primary: Anti-EAAT2 (TMAB-05403) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 62 kDa Observed band size: 66 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Multi-pass membrane protein. |
| Tissue Specificity | Brain |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010] |
| Immunogen | KLH conjugated synthetic peptide: human EAAT2 |
| Antigen Species | Human |
| Gene Name | SLC1A2 |
| Gene ID | |
| Protein Name | Excitatory amino acid transporter 2 |
| Uniprot ID | |
| Function | Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. |
| Molecular Weight | Theoretical: 62 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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