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Anti-TFRC Polyclonal Antibody 3
Catalog No. TMAB-13484 Copy Product Info
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Anti-TFRC Polyclonal Antibody 3 is a Rabbit antibody targeting TFRC. Anti-TFRC Polyclonal Antibody 3 can be used in WB,ELISA.
Anti-TFRC Polyclonal Antibody 3
Copy Product Info🥰Excellent
Catalog No. TMAB-13484
Anti-TFRC Polyclonal Antibody 3 is a Rabbit antibody targeting TFRC. Anti-TFRC Polyclonal Antibody 3 can be used in WB,ELISA.
Anti-TFRC Polyclonal Antibody 3
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-TFRC Polyclonal Antibody 3 is a Rabbit antibody targeting TFRC. Anti-TFRC Polyclonal Antibody 3 can be used in WB,ELISA. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat) |
| Verified Activity | 1. Measured by its binding ability in a indirect ELISA. Immobilized Mouse CD71 protein, His Tag at 2 μg/mL (100 μL/well) can bind Rabbit Anti-Mouse TFRC Antibody, the EC50 is 21.28 ng/mL. 2. Sample: Lane 1: Human HeLa cell lysates Lane 2: Human HT-1080 cell lysates Primary: Anti-TFRC (TMAB-13484) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 74/85 kDa Observed band size: 100 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type II membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015] |
| Immunogen | Recombinant Protein: Mouse CD71 protein |
| Antigen Species | Mouse |
| Gene Name | TFRC |
| Gene ID | |
| Protein Name | Transferrin receptor protein 1 |
| Uniprot ID | |
| Function | Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferring for an overlapping C-terminal binding site. |
| Molecular Weight | Theoretical: 74/85 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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