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Anti-Angiopoietin 4 Polyclonal Antibody

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Catalog No. TMAB-02546

Anti-Angiopoietin 4 Polyclonal Antibody is a Rabbit antibody targeting Angiopoietin 4. Anti-Angiopoietin 4 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Angiopoietin 4 Polyclonal Antibody

Anti-Angiopoietin 4 Polyclonal Antibody

😃Good
Catalog No. TMAB-02546
Anti-Angiopoietin 4 Polyclonal Antibody is a Rabbit antibody targeting Angiopoietin 4. Anti-Angiopoietin 4 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Angiopoietin 4 Polyclonal Antibody is a Rabbit antibody targeting Angiopoietin 4. Anti-Angiopoietin 4 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted (Probable).
Tissue SpecificityHighly expressed in the lung with much lower levels found in other tissues.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundAngiopoietin 4 is a glycosylated protein with a fibrinogen C terminal domain. It is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. Angiopoietin 4 is a serum hormone directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity and also acts as an apoptosis survival factor for vascular endothelial cells. It may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. Alternatively spliced transcript variants encoding different isoforms have been described
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ANGPT4
Antigen Species
Human
Gene Name
ANGPT4
Gene ID
51378
Protein Name
Angiopoietin-4
Uniprot ID
Q9Y264
Function
Binds to TEK/TIE2, modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2. Promotes endothelial cell survival, migration and angiogenesis.
Chemical Properties
Molecular WeightTheoretical: 54 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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