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Anti-IL18R Beta Polyclonal Antibody
😃Good
Catalog No. TMAB-07621
Anti-IL18R Beta Polyclonal Antibody is a Rabbit antibody targeting IL18R Beta. Anti-IL18R Beta Polyclonal Antibody can be used in WB,ELISA.
Anti-IL18R Beta Polyclonal Antibody
Anti-IL18R Beta Polyclonal Antibody
😃Good
Catalog No. TMAB-07621
Anti-IL18R Beta Polyclonal Antibody is a Rabbit antibody targeting IL18R Beta. Anti-IL18R Beta Polyclonal Antibody can be used in WB,ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-IL18R Beta Polyclonal Antibody is a Rabbit antibody targeting IL18R Beta. Anti-IL18R Beta Polyclonal Antibody can be used in WB,ELISA. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon, but not in any other tissue tested. Strongly expressed in T-cells polarized with IL-12. Specifically coexpressed with IL18R1 in Th1 cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | IL18R Beta is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and IL18R Beta is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18. |
| Immunogen | KLH conjugated synthetic peptide: human IL-18R beta |
| Antigen Species | Human |
| Gene Name | IL18RAP |
| Gene ID | |
| Protein Name | Interleukin-18 receptor accessory protein |
| Uniprot ID | |
| Function | Required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex. Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK. |
| Molecular Weight | Theoretical: 68 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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