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Anti-Integrin alpha 6 Polyclonal Antibody
Catalog No. TMAB-07743 Copy Product Info
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Anti-Integrin alpha 6 Polyclonal Antibody is a Rabbit antibody targeting Integrin alpha 6. Anti-Integrin alpha 6 Polyclonal Antibody can be used in WB.
Anti-Integrin alpha 6 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-07743
Anti-Integrin alpha 6 Polyclonal Antibody is a Rabbit antibody targeting Integrin alpha 6. Anti-Integrin alpha 6 Polyclonal Antibody can be used in WB.
Anti-Integrin alpha 6 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Integrin alpha 6 Polyclonal Antibody is a Rabbit antibody targeting Integrin alpha 6. Anti-Integrin alpha 6 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Chicken,Cow) |
| Verified Activity | 1. Sample: Lane 1: SW480 (Human) Cell Lysate at 30 μg Lane 2: A549 (Human) Cell Lysate at 30 μg Lane 3: Huvec (Human) Cell Lysate at 30 μg Lane 4: A431 (Human) Cell Lysate at 30 μg Primary: Anti-Integrin alpha 6 (TMAB-07743) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 120 kD Observed band size: 115 kD 2. Sample: A549 Cell (Human) Lysate at 40 μg Primary: Anti-Integrin alpha 6 (TMAB-07743) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 21/124 kD Observed band size: 130 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoforms containing segment X1 are ubiquitously expressed. Isoforms containing segment X1X2 are expressed in heart, kidney, placenta, colon, duodenum, myoblasts and myotubes, and in a limited number of cell lines; they are always coexpressed with the ubiquitous isoform containing segment X1. In some tissues (e.g. Salivary gland), isoforms containing cytoplasmic segment A and isoforms containing segment B are detected while in others, only isoforms containing one cytoplasmic segment are found (segment A in epidermis and segment B in kidney). |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] |
| Immunogen | KLH conjugated synthetic peptide: human Integrin alpha 6 |
| Antigen Species | Human |
| Gene Name | ITGA6 |
| Gene ID | |
| Protein Name | Integrin alpha-6 |
| Uniprot ID | |
| Function | Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. |
| Molecular Weight | Theoretical: 21/124 kDa. Actual: 120 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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