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Anti-KLF10 Polyclonal Antibody

Catalog No. TMAB-08087 Copy Product Info
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Anti-KLF10 Polyclonal Antibody is a Rabbit antibody targeting KLF10. Anti-KLF10 Polyclonal Antibody can be used in ICC/IF.

Anti-KLF10 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-08087

Anti-KLF10 Polyclonal Antibody is a Rabbit antibody targeting KLF10. Anti-KLF10 Polyclonal Antibody can be used in ICC/IF.

Anti-KLF10 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-KLF10 Polyclonal Antibody is a Rabbit antibody targeting KLF10. Anti-KLF10 Polyclonal Antibody can be used in ICC/IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat)
Verified Activity
Hela cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Antibody incubation with (KLF10) polyclonal Antibody, Unconjugated (TMAB-08087) 1: 25, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue) was used to stain the cell nuclei.
Application
Recommended Dose
ICC/IF: 1:50-200
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundKLF10 is a transcription factor that plays a role in the regulation of cell growth. It binds to the consensus sequence 5'-GGTGTG-3'. KLF10 plays a role in the response to TGFbeta (through the TGFbeta/Smad signalling pathway) and estrogen. In both cases, KLF10 induces or repressed gene transcription to enhance the TGFbeta/Smad signalling pathway, as well as other pathways, to regulate cell proliferation, differentiation and apoptosis. KLF10 has been shown to have a role in skeletal disease (osteopenia/osteoporosis), hypertrophic cardiomyopathy, and breast and prostate cancer.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human TIEG1
Antigen Species
Human
Gene Name
KLF10
Gene ID
Protein Name
Krueppel-like factor 10
Uniprot ID
Function
Transcriptional repressor involved in the regulation of cell growth. Inhibits cell growth. Binds to the consensus sequence 5'-GGTGTG-3'.
Chemical Properties
Molecular WeightTheoretical: 53 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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