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Anti-Hippocalcin Polyclonal Antibody
😃Good
Catalog No. TMAB-07049
Anti-Hippocalcin Polyclonal Antibody is a Rabbit antibody targeting Hippocalcin. Anti-Hippocalcin Polyclonal Antibody can be used in WB.
Anti-Hippocalcin Polyclonal Antibody
Anti-Hippocalcin Polyclonal Antibody
😃Good
Catalog No. TMAB-07049
Anti-Hippocalcin Polyclonal Antibody is a Rabbit antibody targeting Hippocalcin. Anti-Hippocalcin Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Hippocalcin Polyclonal Antibody is a Rabbit antibody targeting Hippocalcin. Anti-Hippocalcin Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Chicken,Cow,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Tissue Specificity | Brain specific. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Hippocalcin is a neuron-specific calcium-binding protein found primarily in the plasma membrane of brain and retinal tissue, with increased expression observed in hippocampal pyramidal cells. Through its calcium-dependent signal regulation, hippocalcin can both inhibit rhodopsin kinase and increase phospholipase D2 expression. In order to regulate kinase and phospholipase activity, hippocalcin must bind to the plasma membrane where it can then bind two calcium ions for use in signal regulation. The hippocalcin protein is highly conserved in mouse, rat and human tissue and has a suggested role in neural plasticity and associative memory by contributing to the survival of neurons during aging. The loss of hippocalcin expression is thought to contribute to age-related impairment of post-synaptic functions related to neuronal degradation. |
| Immunogen | KLH conjugated synthetic peptide: human Hippocalcin |
| Antigen Species | Human |
| Gene Name | HPCA |
| Gene ID | |
| Protein Name | Neuron-specific calcium-binding protein hippocalcin |
| Uniprot ID | |
| Function | May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds two calcium ions. |
| Molecular Weight | Theoretical: 22 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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