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Anti-FDFT1 Polyclonal Antibody

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Catalog No. TMAB-05955

Anti-FDFT1 Polyclonal Antibody is a Rabbit antibody targeting FDFT1. Anti-FDFT1 Polyclonal Antibody can be used in WB.

Anti-FDFT1 Polyclonal Antibody

Anti-FDFT1 Polyclonal Antibody

😃Good
Catalog No. TMAB-05955
Anti-FDFT1 Polyclonal Antibody is a Rabbit antibody targeting FDFT1. Anti-FDFT1 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-FDFT1 Polyclonal Antibody is a Rabbit antibody targeting FDFT1. Anti-FDFT1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Dog)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum membrane.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundSeveral proteins mediate the biosynthesis of cholesterol. The first specific step in the cholesterol biosynthetic pathway is the conversion of transfarnesyl-diphosphate to Squalene, which is catalyzed by the endoplasmic reticulum membrane-associated enzyme Squalene synthetase, also designated Squalene synthase and Farnesyl-diphosphate farnesyltransferase. Squalene synthetase is located at a branch point in the mevalonate pathway and is also involved in isoprenoid biosynthesis. Squalene epoxidase, also designated Squalene monooxygenase, is a multi-pass microsomal membrane-associated enzyme that catalyzes the first oxygenation step in sterol biosynthesis and most likely functions as one of the rate-limiting enzymes in this pathway. Squalene epoxidase may form a complex with Squalene synthetase.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human FDFT1
Antigen Species
Human
Gene Name
FDFT1
Gene ID
Protein Name
Squalene synthase
Uniprot ID
Function
Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.
Chemical Properties
Molecular WeightTheoretical: 48 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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