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Anti-NCAM2 Polyclonal Antibody

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Catalog No. TMAB-09270

Anti-NCAM2 Polyclonal Antibody is a Rabbit antibody targeting NCAM2. Anti-NCAM2 Polyclonal Antibody can be used in FCM.

Anti-NCAM2 Polyclonal Antibody

Anti-NCAM2 Polyclonal Antibody

😃Good
Catalog No. TMAB-09270
Anti-NCAM2 Polyclonal Antibody is a Rabbit antibody targeting NCAM2. Anti-NCAM2 Polyclonal Antibody can be used in FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-NCAM2 Polyclonal Antibody is a Rabbit antibody targeting NCAM2. Anti-NCAM2 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Rabbit)
Application
FCM
Recommended Dose
FCM: 3μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane.
Tissue SpecificityExpressed most strongly in adult and fetal brain.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundNCAM2 is an 837 amino acid protein encoded by the human gene NCAM2. NCAM2 contains five immunoglobulin-like domains, two Fibronectin type III domains, a transmembrane domain and a cytoplasmic domain. The gene is expressed most strongly in human adult and fetal brain. NCAM2 is a member of the neural cell adhesion molecule (NCAM) family. NCAMs are closely related cell surface glycoproteins involved in cell to cell interactions during growth and are thought to play an important role in embryogenesis and development. NCAM2 is a considered a good candidate for involvement in certain Down syndrome phenotypes because a slight overexpression of NCAMs increases many-fold the homotypic adhesion properties of cells. Stat5 regulates NCAM2 in vivo by binding to the NCAM2 intron in the NKL natural killer cell line; this binding is induced by cytokines that activate Stat5. Neither Stat1 nor Stat3 bind to this region, despite sharing a consensus binding sequence with Stat5.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human NCAM2
Antigen Species
Human
Gene Name
NCAM2
Gene ID
4685
Protein Name
Neural cell adhesion molecule 2
Uniprot ID
O15394
Function
May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons.
Chemical Properties
Molecular WeightTheoretical: 91 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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