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Anti-GIYD2 Polyclonal Antibody

Catalog No. TMAB-06490 Copy Product Info
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Anti-GIYD2 Polyclonal Antibody is a Rabbit antibody targeting GIYD2. Anti-GIYD2 Polyclonal Antibody can be used in WB.

Anti-GIYD2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-06490

Anti-GIYD2 Polyclonal Antibody is a Rabbit antibody targeting GIYD2. Anti-GIYD2 Polyclonal Antibody can be used in WB.

Anti-GIYD2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GIYD2 Polyclonal Antibody is a Rabbit antibody targeting GIYD2. Anti-GIYD2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Cow,Horse)
Verified Activity
Sample: A431 (Human) Cell Lysate at 30 μg
Primary: Anti-GIYD2 (TMAB-06490) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 31 kD
Observed band size: 31 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication; this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human GIYD2
Antigen Species
Human
Gene Name
SLX1A
Gene ID
Protein Name
Structure-specific endonuclease subunit SLX1
Uniprot ID
Function
Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.
Chemical Properties
Molecular WeightTheoretical: 31 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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