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Anti-CLN5 Polyclonal Antibody

Catalog No. TMAB-04460 Copy Product Info
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Anti-CLN5 Polyclonal Antibody is a Rabbit antibody targeting CLN5. Anti-CLN5 Polyclonal Antibody can be used in WB.

Anti-CLN5 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-04460

Anti-CLN5 Polyclonal Antibody is a Rabbit antibody targeting CLN5. Anti-CLN5 Polyclonal Antibody can be used in WB.

Anti-CLN5 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CLN5 Polyclonal Antibody is a Rabbit antibody targeting CLN5. Anti-CLN5 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep)
Verified Activity
1. Sample:
Hela (Human) Cell Lysate at 30 μg
HL60 (Human) Cell Lysate at 30 μg
Primary: Anti-CLN5 (TMAB-04460) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 37 kD
2. Sample:
293T (Human) Cell Lysate at 30 μg
Primary: Anti-CLN5 (TMAB-04460) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 37 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationLysosome.
Tissue SpecificityUbiquitous.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundNeuronal ceroid-lipofuscinose (NCL), also designated Batten disease, comprises a group of recessively inherited, progressive neurodegenerative diseases found in children. NCL is characterized by atrophy of the brain and an accumulation of lysosome derived fluorescent bodies found in many cells, especially neurons. Symptoms of NCL include a failure of psychomotor development, seizures, impaired vision and premature death. The eight genes/proteins associated with NCL are designated CLN1-CLN8. Mutations in six of these genes results in a distinct type of NCL-disease; the six genes/proteins are CLN1 (encoding PPT1, a protein thiolesterase), CLN2 (encodeing the serine protease TPP1), CLN3, CLN5, CLN6 and CLN8. A single base duplication mutation in dog and cow CLN5 has been shown to cause NCL.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CLN5
Antigen Species
Human
Gene Name
CLN5
Gene ID
Protein Name
Ceroid-lipofuscinosis neuronal protein 5
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 37 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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