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Anti-Phospho-MKP1 (Ser359) Polyclonal Antibody
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Catalog No. TMAB-10998
Anti-Phospho-MKP1 (Ser359) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MKP1 (Ser359). Anti-Phospho-MKP1 (Ser359) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Phospho-MKP1 (Ser359) Polyclonal Antibody
Anti-Phospho-MKP1 (Ser359) Polyclonal Antibody
😃Good
Catalog No. TMAB-10998
Anti-Phospho-MKP1 (Ser359) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MKP1 (Ser359). Anti-Phospho-MKP1 (Ser359) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
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Antigen Details
Chemical Properties
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| Description | Anti-Phospho-MKP1 (Ser359) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MKP1 (Ser359). Anti-Phospho-MKP1 (Ser359) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Chicken,Dog,Pig,Cow,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Tissue Specificity | Expressed at high levels in the lung, liver placenta and pancreas. Moderate levels seen in the heart and skeletal muscle. Lower levels found in the brain and kidney. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. |
| Immunogen | KLH conjugated synthesised phosphopeptide: human MKP1 around the phosphorylation site of Ser359 |
| Antigen Species | Human |
| Gene Name | DUSP1 |
| Gene ID | |
| Protein Name | Dual specificity protein phosphatase 1 |
| Uniprot ID | |
| Function | Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185'. |
| Molecular Weight | Theoretical: 40 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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