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Anti-DMRTA2 Polyclonal Antibody is a Rabbit antibody targeting DMRTA2. Anti-DMRTA2 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-DMRTA2 Polyclonal Antibody is a Rabbit antibody targeting DMRTA2. Anti-DMRTA2 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Pig,Cow) |
| Verified Activity | Sample: Lane 1: Human Jurkat cell lysates Lane 2: Human SH-SY5Y cell lysates Lane 3: Human U-2 OS cell lysates Primary: Anti-DMRTA2 (TMAB-05207) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kDa Observed band size: 54 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Expressed in testis. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | DMRTA2 is a 542 amino acid protein that localizes to the nucleus and contains one DM DNA-binding domain. Expressed testis, DMRTA2 is thought to be involved in sexual developmental processes during maturation. The gene encoding DMRTA2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
| Immunogen | KLH conjugated synthetic peptide: human DMRTA2 |
| Antigen Species | Human |
| Gene Name | DMRTA2 |
| Gene ID | |
| Protein Name | Doublesex-and mab-3-related transcription factor A2 |
| Uniprot ID | |
| Function | May be involved in sexual development. |
| Molecular Weight | Theoretical: 53 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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