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Anti-A4GALT Polyclonal Antibody 2
(Synonyms: UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase, UDP galactose beta D galactosyl beta1 R 4 alpha D galactosyltransferase, PK, P1/Pk synthase, P1, P(k) antigen synthase, P blood group(P one antigen), Lactosylceramide 4-alpha-galactosyltransferase, Lactosylceramide 4 alpha galactosyltransferase, Globotriaosylceramide synthase, Gb3S, GB3 synthase, CD77 synthase, alpha4Gal-T1, alpha4Gal T1, alpha-1, alpha 1 4 N acetylglucosaminyltransferase, alpha 1 4 galactosyltransferase, A4GAT_HUMAN, A4GALT1, A14GALT, 4-N-acetylglucosaminyltransferase, 4-galactosyltransferase, 4 N acetylglucosaminyltransferase) Copy Product Info
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Synonyms: UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase, UDP galactose beta D galactosyl beta1 R 4 alpha D galactosyltransferase, PK, P1/Pk synthase, P1, P(k) antigen synthase, P blood group(P one antigen), Lactosylceramide 4-alpha-galactosyltransferase, Lactosylceramide 4 alpha galactosyltransferase, Globotriaosylceramide synthase, Gb3S, GB3 synthase, CD77 synthase, alpha4Gal-T1, alpha4Gal T1, alpha-1, alpha 1 4 N acetylglucosaminyltransferase, alpha 1 4 galactosyltransferase, A4GAT_HUMAN, A4GALT1, A14GALT, 4-N-acetylglucosaminyltransferase, 4-galactosyltransferase, 4 N acetylglucosaminyltransferase
Catalog No. TMAB-02121 Copy Product Info
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Anti-A4GALT Polyclonal Antibody 2 is a Rabbit antibody targeting A4GALT. Anti-A4GALT Polyclonal Antibody 2 can be used in FCM.
Anti-A4GALT Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Antigen Details
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| Description | Anti-A4GALT Polyclonal Antibody 2 is a Rabbit antibody targeting A4GALT. Anti-A4GALT Polyclonal Antibody 2 can be used in FCM. |
| Synonyms | UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase, UDP galactose beta D galactosyl beta1 R 4 alpha D galactosyltransferase, PK, P1/Pk synthase, P1, P(k) antigen synthase, P blood group(P one antigen), Lactosylceramide 4-alpha-galactosyltransferase, Lactosylceramide 4 alpha galactosyltransferase, Globotriaosylceramide synthase, Gb3S, GB3 synthase, CD77 synthase, alpha4Gal-T1, alpha4Gal T1, alpha-1, alpha 1 4 N acetylglucosaminyltransferase, alpha 1 4 galactosyltransferase, A4GAT_HUMAN, A4GALT1, A14GALT, 4-N-acetylglucosaminyltransferase, 4-galactosyltransferase, 4 N acetylglucosaminyltransferase |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Chicken,Dog,Pig) |
| Application | |
| Recommended Dose | FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Golgi apparatus membrane; Single-pass type II membrane protein (Probable). |
| Tissue Specificity | Ubiquitous. Highly expressed in kidney, heart, spleen, liver, testis and placenta. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins.Expression of CD77, also called Gb3, sensitizes a cell to verotoxins, causing cellular injury that can lead to disease. Therefore, the complex regulation of CD77 biosynthesis and the activity of the enzymes involved, such as CD77 synthase, can be studied by compared gene expression between toxin-sensitive and insensitive tissues and cell lines. The highest tissue expression of CD77 synthase occurs in the kidney, mesenteric lymph node, spleen, and brain. Burkitt leukemia cells express very high levels of CD77 as well as CD77 synthase, and are sensitive to verotoxin induced apoptosis. These megakaryoblasts then never mature, leading to the arrest of platelet generation in the bone marrow, which may cause thrombocytopenia, a symptom associated with various hemorrhagic conditions. |
| Immunogen | KLH conjugated synthetic peptide: human A4GALT/CD77 |
| Antigen Species | Human |
| Gene Name | A4GALT |
| Gene ID | |
| Protein Name | Lactosylceramide 4-alpha-galactosyltransferase |
| Uniprot ID | |
| Function | Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins. |
| Molecular Weight | Theoretical: 40 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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