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Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody

Catalog No. TMAB-11159 Copy Product Info
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Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKMYT1 (Ser83). Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody can be used in WB.

Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-11159

Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKMYT1 (Ser83). Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody can be used in WB.

Anti-Phospho-PKMYT1
(Ser83) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKMYT1 (Ser83). Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Horse)
Verified Activity
Sample: A431 (Human) Cell Lysate at 30 μg
Primary: Anti-Phospho-PKMYT1 (Ser83) (TMAB-11159) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kD
Observed band size: 54 kD
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum membrane. Golgi apparatus membrane.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a member of the serine/threonine protein kinase family. The encoded protein is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1. The activity of the encoded protein is regulated by polo-like kinase 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Antigen Details
Immunogen
KLH conjugated synthesised phosphopeptide: human PKMYT1 around the phosphorylation site of Ser83
Antigen Species
Human
Gene Name
PKMYT1
Gene ID
9088
Protein Name
Membrane-associated tyrosine-and threonine-specific cdc2-inhibitory kinase
Uniprot ID
Q99640
Function
Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.
Chemical Properties
Molecular WeightTheoretical: 54 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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