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Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody
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Catalog No. TMAB-11159
Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKMYT1 (Ser83). Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody can be used in WB.
Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody
Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody
😃Good
Catalog No. TMAB-11159
Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKMYT1 (Ser83). Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKMYT1 (Ser83). Anti-Phospho-PKMYT1 (Ser83) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Horse) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum membrane. Golgi apparatus membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the serine/threonine protein kinase family. The encoded protein is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1. The activity of the encoded protein is regulated by polo-like kinase 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012] |
| Immunogen | KLH conjugated synthesised phosphopeptide: human PKMYT1 around the phosphorylation site of Ser83 |
| Antigen Species | Human |
| Gene Name | PKMYT1 |
| Gene ID | |
| Protein Name | Membrane-associated tyrosine-and threonine-specific cdc2-inhibitory kinase |
| Uniprot ID | |
| Function | Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development. |
| Molecular Weight | Theoretical: 54 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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