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Anti-AGT Monoclonal Antibody (Synonyms: Serpin A8, Angiotensinogen)
Catalog No. TMAZ-0159 Copy Product Info
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Anti-AGT Monoclonal Antibody is a humanized rabbit antibody targeting AGT. Anti-AGT Monoclonal Antibody can be used in ELISA,FCM.
Anti-AGT Monoclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAZ-0159
Synonyms Serpin A8, Angiotensinogen
Anti-AGT Monoclonal Antibody is a humanized rabbit antibody targeting AGT. Anti-AGT Monoclonal Antibody can be used in ELISA,FCM.
Anti-AGT Monoclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μg | $196 | 12 days | 12 days | |
| 50 μg | $236 | 12 days | 12 days | |
| 100 μg | $330 | 12 days | 12 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Related Conjugates and Formulations
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| Description | Anti-AGT Monoclonal Antibody is a humanized rabbit antibody targeting AGT. Anti-AGT Monoclonal Antibody can be used in ELISA,FCM. |
| Synonyms | Serpin A8, Angiotensinogen |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of AGT overexpressed 435F cells with TMAZ-0159, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of AGT protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in PBS. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis|Acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone (PubMed: 10619573, PubMed: 17138938). Acts by binding to angiotensin receptors AGTR1 and AGTR2 (PubMed: 1567413). Also binds the DEAR/FBXW7-AS1 receptor (By similarity)|Stimulates aldosterone release|Is a ligand for the G-protein coupled receptor MAS1 (By similarity). Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets (By similarity) |
| Conjucates | Unconjugated |
| Others Formats | Biotin |
| Antibody Types Available | 2 |
| Immunogen | AGT |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Drug Target |
| Molecular Weight | 150 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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