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Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody
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Catalog No. TMAB-10703 Copy Product Info
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Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FHOD1 (Thr1141). Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-Phospho-FHOD1
(Thr1141) Polyclonal Antibody
(Thr1141) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FHOD1 (Thr1141). Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Cytoplasm > cytoskeleton. Predominantly cytoplasmic. |
| Tissue Specificity | Ubiquitous. Highly expressed in spleen. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of protein products known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing actin filament assembly. The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. FHOD1 induces the formation of and associates with bundled actin stress fibers in response to the activity of the Rho-ROCK cascade. It influences several cellular activities including cell migration, cytoskeletal arrangement, signal transduction and gene expression. |
| Immunogen | KLH conjugated synthesised phosphopeptide: human FHOD1 around the phosphorylation site of Thr1141 |
| Antigen Species | Human |
| Gene Name | FHOD1 |
| Gene ID | |
| Protein Name | FH1/FH2 domain-containing protein 1 |
| Uniprot ID | |
| Function | Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. |
| Molecular Weight | Theoretical: 126 kDa. Actual: 126 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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