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Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody

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Catalog No. TMAB-10703

Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FHOD1 (Thr1141). Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody

Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody

😃Good
Catalog No. TMAB-10703
Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FHOD1 (Thr1141). Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FHOD1 (Thr1141). Anti-Phospho-FHOD1 (Thr1141) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit)
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Cytoplasm > cytoskeleton. Predominantly cytoplasmic.
Tissue SpecificityUbiquitous. Highly expressed in spleen.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of protein products known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing actin filament assembly. The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. FHOD1 induces the formation of and associates with bundled actin stress fibers in response to the activity of the Rho-ROCK cascade. It influences several cellular activities including cell migration, cytoskeletal arrangement, signal transduction and gene expression.
Antigen Details
Immunogen
KLH conjugated synthesised phosphopeptide: human FHOD1 around the phosphorylation site of Thr1141
Antigen Species
Human
Gene Name
FHOD1
Gene ID
Protein Name
FH1/FH2 domain-containing protein 1
Uniprot ID
Function
Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation.
Chemical Properties
Molecular WeightTheoretical: 126 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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