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Anti-LAR Polyclonal Antibody

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Catalog No. TMAB-08219 Copy Product Info
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Anti-LAR Polyclonal Antibody is a Rabbit antibody targeting LAR. Anti-LAR Polyclonal Antibody can be used in FCM.
Anti-LAR Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-LAR Polyclonal Antibody is a Rabbit antibody targeting LAR. Anti-LAR Polyclonal Antibody can be used in FCM.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep)
Application
Recommended Dose
FCM: 1μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PTPRF
Antigen Species
Human
Gene Name
PTPRF
Gene ID
Protein Name
Receptor-type tyrosine-protein phosphatase F
Uniprot ID
Function
Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity.
The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.
Chemical Properties
Molecular WeightTheoretical: 210 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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