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Anti-GNAQ Polyclonal Antibody
Catalog No. TMAB-06603 Copy Product Info
🥰Excellent
Anti-GNAQ Polyclonal Antibody is a Rabbit antibody targeting GNAQ. Anti-GNAQ Polyclonal Antibody can be used in WB.
Anti-GNAQ Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-06603
Anti-GNAQ Polyclonal Antibody is a Rabbit antibody targeting GNAQ. Anti-GNAQ Polyclonal Antibody can be used in WB.
Anti-GNAQ Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GNAQ Polyclonal Antibody is a Rabbit antibody targeting GNAQ. Anti-GNAQ Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| Verified Activity | 1. Sample: Ovary (Mouse) Lysate at 40 μg Primary: Anti-GNAQ (TMAB-06603) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 42 kD 2. Sample: Uterus (Mouse) Lysate at 40 μg Primary: Anti-GNAQ (TMAB-06603) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 42 kD 3. Sample: SY5Y (Human) Cell Lysate at 30 μg Primary: Anti-GNAQ (TMAB-06603) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 42 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus (By similarity). Membrane (By similarity). Nucleus membrane (By similarity). Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes (By similarity). |
| Tissue Specificity | Predominantly expressed in ovary, prostate, testis and colon. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | GNAQ belong to the family of heterotrimeric Guanine nucleotide-binding proteins proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. GNAQ is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta. in recent studies over expression of GNAQ is associated with cardiomyocyte apoptosis. |
| Immunogen | KLH conjugated synthetic peptide: human GNAQ |
| Antigen Species | Human |
| Gene Name | GNAQ |
| Gene ID | |
| Protein Name | Guanine nucleotide-binding protein G(q) subunit alpha |
| Uniprot ID | |
| Function | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity). |
| Molecular Weight | Theoretical: 42 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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